POIS-News
Postorgasmic-Illness-Syndrome News
POIS-News provides the latest news, research findings, and testimonials relating to postorgasmic-llness-syndrome. Here you can find news about studies, therapies, self-help services, and events—presented in a concise and easy-to-understand format.
Subscribe to our newsletter!
- POIS Is Not the Same for Everyone: New Study Identifies Four Possible PhenotypesPost-Orgasmic Illness Syndrome (POIS) can present very differently from one person to another. While some affected individuals primarily experience severe fatigue, cognitive problems and flu-like symptoms after ejaculation, others report predominantly nasal symptoms, mood changes, headaches or muscle pain. This considerable variation has long raised an important question: Is POIS… Read more: POIS Is Not the Same for Everyone: New Study Identifies Four Possible Phenotypes
- Mast Cells and the Immune System in POIS: New Review Explores Possible MechanismsWhy do people with Post-Orgasmic Illness Syndrome (POIS) develop symptoms such as fatigue, brain fog, muscle pain, nasal congestion, or flu-like symptoms after ejaculation or orgasm? The underlying cause of this rare condition remains unknown. Since the first scientific descriptions of POIS, researchers have repeatedly discussed a possible involvement of… Read more: Mast Cells and the Immune System in POIS: New Review Explores Possible Mechanisms
- New Case Report: Sertraline May Help Some Patients With Postorgasmic-Illness-SyndromeA newly published case report in The Journal of Sexual Medicine describes two men with postorgasmic-illness-syndrome (POIS) whose symptoms improved significantly after treatment with sertraline. The authors suggest that serotonergic mechanisms may play a role in at least some forms of the condition. Two Patients, Similar Symptoms The report presents… Read more: New Case Report: Sertraline May Help Some Patients With Postorgasmic-Illness-Syndrome
- One year POIS-Network: Growing demand for informationpostorgasmic-illness-syndrome One year POIS-Network Growing demand for information 2025 marked the first full calendar year of activity for POIS-Network. Between January 1 and December 31, the platforms POIS-Network and POIS-Deutschland together reached nearly 5,000 users worldwide, generating approximately 30,000 interactions. For a rare and still largely unknown condition, these figures… Read more: One year POIS-Network: Growing demand for information
- New Case Reports Highlight Clinical Heterogeneity and Gaps in Care in Postorgasmic-Illness-SyndromeA new study from Portugal (preprint) presents two detailed case reports on Postorgasmic-Illness-Syndrome (POIS), providing important insights into the clinical heterogeneity, therapeutic challenges, and psychosocial burden of the condition. The paper describes two men with POIS who developed not only physical symptoms such as extreme fatigue, muscle-related complaints, and cognitive… Read more: New Case Reports Highlight Clinical Heterogeneity and Gaps in Care in Postorgasmic-Illness-Syndrome